CR1L

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CR1L mutation is significantly associated with the RNA expression of many other genes, with 1,444 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CR1L-associated genes across cancer lineages are SNORD116-22, SUSD2, and LINC02143. Each is linked with CR1L in more than 3 cancer types. Because this analysis shows association rather than direction, both CR1L-to-partner and partner-to-CR1L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CR1L→partner) and Y-score (partner→CR1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMSNORD116-22 →+0.193+2.455<.001.00834
UCECSUSD2 →-1.104-2.000<.001.00332
SKCMLINC02143 →+0.024+2.961.002.00232
HNSCRNY3P11 →+0.463+6.090<.001<.00132
HNSCMIR624 →+0.608+4.916<.001.00232
HNSCMIR620 →+0.398+5.608<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,444 associations by consensus.

Exploration