Across TCGA cell cohorts, CR1L mutation is significantly associated with the RNA expression of many other genes, with 40 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CR1L-associated genes across cancer lineages are CLNK, TTLL8, and MEI4. Each is linked with CR1L in more than 1 cancer types. Because this analysis shows association rather than direction, both CR1L-to-partner and partner-to-CR1L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CR1L→partner) and Y-score (partner→CR1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CLNK →	+0.021	+3.969	.008	.004	3	1
LARGE_INTESTINE	TTLL8 →	+0.003	+4.022	<.001	.006	3	1
LARGE_INTESTINE	MEI4 →	+0.005	+4.099	.002	<.001	3	1
STOMACH	OC90 →	+0.030	+5.285	<.001	.003	3	1
LUNG_NSCLC_LUAD	MAGEB10 →	+0.021	+4.544	.002	.003	3	1
LUNG_NSCLC_LUAD	PRAMEF19 →	+0.012	+4.662	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

Exploration

CR1L survival (RNA) · tumor vs normal (RNA) · all CR1L data types