Across TCGA patient cohorts, CPSF4L mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPSF4L-associated genes across cancer lineages are FAM41AY1, LINC02286, and MIR3678. Each is linked with CPSF4L in more than 1 cancer types. Because this analysis shows association rather than direction, both CPSF4L-to-partner and partner-to-CPSF4L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPSF4L→partner) and Y-score (partner→CPSF4L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	FAM41AY1 →	+0.074	+7.741	<.001	.009	3	1
COAD	LINC02286 →	+0.205	+7.741	<.001	.009	3	1
UCEC	MIR3678 →	+0.489	+5.771	.001	<.001	3	1
UCEC	RNU6-391P →	+0.537	+5.027	<.001	.004	3	1
UCEC	POM121L12 →	+0.034	+5.226	.001	.003	3	1
UCEC	LINC01706 →	+0.108	+4.621	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

CPSF4L survival (RNA) · tumor vs normal (RNA) · all CPSF4L data types