CPOX

Across TCGA patient cohorts, CPOX RNA expression is significantly associated with the protein abundance of many other proteins, with 12,990 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CPOX-associated proteins across cancer lineages are NUP155, AHSA1, and MCM4. Each is linked with CPOX in more than 3 cancer types. Because this analysis shows association rather than direction, both CPOX-to-partner and partner-to-CPOX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPOX versus NUP155 in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CPOX→partner) and Y-score (partner→CPOX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NUP155 →	+0.191	+0.609	<.001	<.001	3	4
LSCC	AHSA1 →	+0.241	+0.452	.001	.005	3	4
LSCC	MCM4 →	+0.653	+0.475	<.001	<.001	3	4
LSCC	MCM6 →	+0.684	+0.476	<.001	<.001	3	4
LSCC	MCM7 →	+0.632	+0.536	<.001	<.001	3	4
GBM	PLXNA1 →	+0.260	+0.348	.002	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,990 associations by consensus.

CPOX vs NUP155 — LSCC

Explore this scatter interactively →