CPNE3

Across TCGA patient cohorts, CPNE3 mutation is significantly associated with the RNA expression of many other genes, with 1,663 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPNE3-associated genes across cancer lineages are RNU6-591P, RN7SL248P, and MIR4662B. Each is linked with CPNE3 in more than 2 cancer types. Because this analysis shows association rather than direction, both CPNE3-to-partner and partner-to-CPNE3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-591P grouped by CPNE3-low versus CPNE3-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPNE3→partner) and Y-score (partner→CPNE3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	RNU6-591P →	+0.238	+7.939	<.001	.008	3	3
UCEC	RN7SL248P →	+0.057	+3.078	<.001	.001	3	3
STAD	MIR4662B →	+0.691	+4.782	.001	.003	3	3
BRCA	BUD31P1 →	+0.073	+7.731	<.001	.009	3	2
CESC	RNU1-62P →	+0.238	+5.539	<.001	.004	3	2
CESC	SGO1P1 →	+0.032	+6.837	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,663 associations by consensus.

RNU6-591P by CPNE3 expression — PRAD

Explore this box plot interactively →