CPN2

Across TCGA cell cohorts, CPN2 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CPN2-associated genes across cancer lineages are OR10W1, CCL21, and C9orf92. Each is linked with CPN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPN2-to-partner and partner-to-CPN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10W1 grouped by CPN2-low versus CPN2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPN2→partner) and Y-score (partner→CPN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR10W1 →	+0.032	+5.643	<.001	.002	3	2
BLOOD_Lymphoma	CCL21 →	+0.180	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	C9orf92 →	+0.386	+5.643	<.001	.002	3	1
LARGE_INTESTINE	ACER1 →	+0.069	+3.408	.003	<.001	3	1
LARGE_INTESTINE	OR2C1 →	+0.105	+3.047	<.001	.005	3	1
LARGE_INTESTINE	KCNG2 →	+0.116	+3.215	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

OR10W1 by CPN2 expression — BLOOD_Lymphoma

Explore this box plot interactively →