CPEB4

Across TCGA pan-cancer cohorts, CPEB4 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CPEB4 data layer compared with 22 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CPEB4 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated CPEB4 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

UCEC, LUAD, and HNSC are the cancer types where CPEB4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Quartile	All	1.000	0.804	.010	12	view →
LUAD	OS	Tertile	All	0.619	0.888	.041	2	view →
HNSC	OS	Median	All	0.907	0.799	.020	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CPEB4–UCEC (OS)

Open the UCEC breakdown →