CPEB3

Across TCGA patient cohorts, CPEB3 mutation is significantly associated with the total protein of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPEB3-associated genes across cancer lineages are eEF2, FoxM1, and INPP4B. Each is linked with CPEB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPEB3-to-partner and partner-to-CPEB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by CPEB3-low versus CPEB3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPEB3→partner) and Y-score (partner→CPEB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.380	+2.000	.006	.010	3	2
UCEC	FoxM1 →	+0.232	+2.502	.022	.002	3	2
UCEC	INPP4B →	-0.373	-3.584	.003	.002	3	2
UCEC	ASNS →	+0.433	+2.000	.002	.010	3	2
UCEC	Bax →	+0.191	+1.884	.042	.030	3	2
UCEC	C-Raf →	+0.253	+3.169	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

eEF2 by CPEB3 expression — UCEC

Explore this box plot interactively →