CPEB3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CPEB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,159 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CPEB3-associated GO terms across cancer lineages are Golgi vesicle budding, Negative regulation of oxidoreductase activity, and Regulation of cytoplasmic mRNA processing body assembly. Each is linked with CPEB3 in more than 10 cancer types. Because this analysis shows association rather than direction, both CPEB3-to-partner and partner-to-CPEB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle budding grouped by CPEB3-low versus CPEB3-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPEB3→partner) and Y-score (partner→CPEB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEGolgi vesicle budding →+0.112+0.504.001<.001311
URINARY_TRACTNegative regulation of oxidoreductase activity →-0.184-0.552<.001.001310
BLOOD_LymphomaRegulation of cytoplasmic mRNA processing body assembly →+0.109+0.542<.001.001310
STOMACHRegulation of cytoplasmic translational elongation →-0.189-0.745.003.001210
BLOOD_LeukemiaPost-Golgi vesicle-mediated transport →+0.052+0.413<.001<.00139
BREASTFlagellated sperm motility →-0.084-0.503<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,159 associations by consensus.

Golgi vesicle budding by CPEB3 expression — LARGE_INTESTINE

Box plot of Golgi vesicle budding in CPEB3-low vs CPEB3-high samples in LARGE_INTESTINE.

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Exploration