CPEB3

Across TCGA cell cohorts, CPEB3 mutation is significantly associated with the RNA expression of many other genes, with 657 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CPEB3-associated genes across cancer lineages are MAGEB10, GCAT, and CCDC134. Each is linked with CPEB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPEB3-to-partner and partner-to-CPEB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB10 grouped by CPEB3-low versus CPEB3-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPEB3→partner) and Y-score (partner→CPEB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	MAGEB10 →	+0.040	+4.228	<.001	.006	3	2
LARGE_INTESTINE	GCAT →	+1.422	+3.628	<.001	<.001	3	1
LARGE_INTESTINE	CCDC134 →	+0.756	+3.301	.001	.003	3	1
LARGE_INTESTINE	CBY1 →	+0.712	+2.588	<.001	.004	3	1
LARGE_INTESTINE	JOSD1 →	+0.517	+3.169	.004	.006	3	1
LARGE_INTESTINE	HMGXB4 →	+0.586	+3.628	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 657 associations by consensus.

MAGEB10 by CPEB3 expression — OVARY

Explore this box plot interactively →