Across TCGA cell cohorts, CPEB1 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CPEB1-associated genes across cancer lineages are PRAMEF18, OOSP4A, and ACTRT1. Each is linked with CPEB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPEB1-to-partner and partner-to-CPEB1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPEB1→partner) and Y-score (partner→CPEB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	PRAMEF18 →	+0.026	+4.930	<.001	.008	3	1
SOFT_TISSUE	OOSP4A →	+0.053	+4.930	<.001	.008	3	1
OESOPHAGUS	ACTRT1 →	+0.023	+4.906	<.001	.006	3	1
OESOPHAGUS	BMP15 →	+0.030	+4.906	<.001	.006	3	1
OESOPHAGUS	WFDC8 →	+0.020	+4.906	<.001	.006	3	1
LARGE_INTESTINE	ITGAD →	+0.015	+4.095	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

CPEB1 survival (RNA) · tumor vs normal (RNA) · all CPEB1 data types