Across TCGA cell cohorts, CPEB1 mutation is significantly associated with the mutation status of many other genes, with 2,526 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CPEB1-associated genes across cancer lineages are GRM3, BRPF3, and SETD1A. Each is linked with CPEB1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CPEB1-to-partner and partner-to-CPEB1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPEB1→partner) and Y-score (partner→CPEB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	GRM3 →	+4.316	+3.832	.002	.002	1	5
BLOOD_Lymphoma	BRPF3 →	+3.731	+3.938	<.001	<.001	1	4
BLOOD_Lymphoma	SETD1A →	+3.146	+3.584	.001	.001	1	4
LUNG_NSCLC_LUAD	KCNG4 →	+5.000	+4.187	.008	.008	1	4
LUNG_NSCLC_LUAD	ZNF608 →	+3.263	+3.851	.005	.005	1	4
CNS	RAPGEF4 →	+4.044	+5.000	.008	.008	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,526 associations by consensus.

Exploration

CPEB1 survival (RNA) · tumor vs normal (RNA) · all CPEB1 data types