COX7C

Across TCGA patient cohorts, COX7C mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible COX7C-associated genes across cancer lineages are RNU6-668P, OFD1P10Y, and RNU1-77P. Each is linked with COX7C in more than 1 cancer types. Because this analysis shows association rather than direction, both COX7C-to-partner and partner-to-COX7C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-668P grouped by COX7C-low versus COX7C-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX7C→partner) and Y-score (partner→COX7C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-668P →	+0.228	+7.816	<.001	.008	3	1
SKCM	OFD1P10Y →	+0.019	+7.816	<.001	.008	3	1
UCEC	RNU1-77P →	+0.580	+5.081	.003	.008	3	1
SKCM	RN7SL601P →	+0.249	+7.816	<.001	.008	3	1
SKCM	RNU2-53P →	+0.434	+7.816	<.001	.008	3	1
SKCM	MIR3118-1 →	+0.303	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

RNU6-668P by COX7C expression — SKCM

Explore this box plot interactively →