COX7C

Across TCGA cell cohorts, COX7C RNA expression is significantly associated with the go_rna of many other GO terms, with 3,747 significant associations in total. BONE shows the largest number of these associations.

The most reproducible COX7C-associated GO terms across cancer lineages are Mitochondrial translation, Dihydrofolate metabolic process, and NADH dehydrogenase complex assembly. Each is linked with COX7C in more than 10 cancer types. Because this analysis shows association rather than direction, both COX7C-to-partner and partner-to-COX7C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial translation grouped by COX7C-low versus COX7C-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COX7C→partner) and Y-score (partner→COX7C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mitochondrial translation →	+0.105	+0.829	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Dihydrofolate metabolic process →	+0.213	+1.064	.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	NADH dehydrogenase complex assembly →	+0.086	+0.762	.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Mitochondrial respiratory chain complex I assembly →	+0.086	+0.762	.001	<.001	3	10
BONE	Cell-substrate adhesion →	-0.133	-0.944	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Ketone metabolic process →	+0.074	+0.597	.001	.006	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,747 associations by consensus.

Mitochondrial translation by COX7C expression — BONE

Explore this box plot interactively →