COX5B

Across TCGA cell cohorts, COX5B RNA expression is significantly associated with the RNA expression of many other genes, with 7,739 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible COX5B-associated genes across cancer lineages are NDUFA1, ATP5ME, and COX6A1. Each is linked with COX5B in more than 14 cancer types. Because this analysis shows association rather than direction, both COX5B-to-partner and partner-to-COX5B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COX5B versus NDUFA1 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.59.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX5B→partner) and Y-score (partner→COX5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	NDUFA1 →	+1.081	+1.046	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	ATP5ME →	+1.166	+0.939	<.001	<.001	3	14
BLOOD_Myeloma	COX6A1 →	+1.038	+0.807	<.001	.002	3	14
BREAST	COX7B →	+1.245	+0.785	<.001	<.001	3	14
BLOOD_Myeloma	NDUFB3 →	+1.091	+1.008	<.001	<.001	3	12
URINARY_TRACT	NDUFB4 →	+1.059	+0.943	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,739 associations by consensus.

COX5B vs NDUFA1 — UPPER_AERODIGESTIVE_TRACT

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