COX17

Across TCGA patient cohorts, COX17 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COX17-associated genes across cancer lineages are RN7SL248P, RPS29P32, and SNORD116-10. Each is linked with COX17 in more than 1 cancer types. Because this analysis shows association rather than direction, both COX17-to-partner and partner-to-COX17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by COX17-low versus COX17-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX17→partner) and Y-score (partner→COX17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.212	+5.722	<.001	.001	3	2
UCEC	RPS29P32 →	+1.110	+5.184	<.001	.001	3	1
UCEC	SNORD116-10 →	+0.518	+5.335	<.001	.003	3	1
UCEC	RNA5SP30 →	+0.829	+4.778	<.001	.003	3	1
UCEC	RNU2-50P →	+0.702	+4.423	.001	.006	3	1
UCEC	RNA5SP451 →	+0.805	+4.852	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

RN7SL248P by COX17 expression — UCEC

Explore this box plot interactively →