COX10

Across TCGA patient cohorts, COX10 mutation is significantly associated with the RNA expression of many other genes, with 2,656 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COX10-associated genes across cancer lineages are RNU4-58P, IQCF5, and OR7E37P. Each is linked with COX10 in more than 2 cancer types. Because this analysis shows association rather than direction, both COX10-to-partner and partner-to-COX10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-58P grouped by COX10-low versus COX10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX10→partner) and Y-score (partner→COX10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU4-58P →	+0.183	+2.396	<.001	.001	3	3
KIRP	IQCF5 →	+0.092	+4.770	<.001	.006	3	2
KIRP	OR7E37P →	+0.050	+4.830	<.001	.002	3	2
LUSC	CTNNA2-AS1 →	+0.292	+4.606	<.001	.006	3	2
BLCA	RNU6-552P →	+0.485	+5.106	<.001	.008	3	2
STAD	RNU6-480P →	+0.341	+4.678	.002	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,656 associations by consensus.

RNU4-58P by COX10 expression — UCEC

Explore this box plot interactively →