CORO7-PAM16

Across TCGA patient cohorts, CORO7-PAM16 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,533 significant associations in total. OV shows the largest number of these associations.

The most reproducible CORO7-PAM16-associated GO terms across cancer lineages are Negative regulation of protein localization to chromatin, Positive regulation of T-helper 17 type immune response, and Secretion of lysosomal enzymes. Each is linked with CORO7-PAM16 in more than 13 cancer types. Because this analysis shows association rather than direction, both CORO7-PAM16-to-partner and partner-to-CORO7-PAM16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein localization to chromatin grouped by CORO7-PAM16-low versus CORO7-PAM16-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CORO7-PAM16→partner) and Y-score (partner→CORO7-PAM16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Negative regulation of protein localization to chromatin →	+0.042	+0.056	<.001	<.001	3	13
LAML	Positive regulation of T-helper 17 type immune response →	+0.046	+0.053	.003	.001	2	14
LAML	Secretion of lysosomal enzymes →	+0.050	+0.082	.001	<.001	2	13
GBM	Virion assembly →	+0.020	+0.045	<.001	.002	3	12
LUSC	Methylglyoxal metabolic process →	+0.038	+0.033	<.001	<.001	3	12
LUAD	Positive regulation of regulatory T cell differentiation →	+0.034	+0.028	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,533 associations by consensus.

Negative regulation of protein localization to chromatin by CORO7-PAM16 expression — LAML

Explore this box plot interactively →