COQ3

Across TCGA patient cohorts, COQ3 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,843 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COQ3-associated proteins across cancer lineages are RRM2, SMC2, and SMC4. Each is linked with COQ3 in more than 7 cancer types. Because this analysis shows association rather than direction, both COQ3-to-partner and partner-to-COQ3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COQ3 versus RRM2 in UCEC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COQ3→partner) and Y-score (partner→COQ3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RRM2 →	+0.650	+0.693	<.001	<.001	3	8
BRCA	SMC2 →	+0.625	+0.613	<.001	<.001	3	8
GBM	SMC4 →	+0.478	+0.349	.002	.002	3	8
BRCA	CDC40 →	+0.271	+0.643	<.001	<.001	3	8
LUAD	KIF11_T926 →	+0.870	+0.361	.001	<.001	3	8
BRCA	NASP →	+0.561	+0.531	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,843 associations by consensus.

COQ3 vs RRM2 — UCEC

Explore this scatter interactively →