COPS8P3

Across TCGA patient cohorts, COPS8P3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,190 significant associations in total. STAD shows the largest number of these associations.

The most reproducible COPS8P3-associated GO terms across cancer lineages are tRNA threonylcarbamoyladenosine modification, Obsolete ubiquitin-dependent ERAD pathway, and Regulation of DNA strand elongation. Each is linked with COPS8P3 in more than 10 cancer types. Because this analysis shows association rather than direction, both COPS8P3-to-partner and partner-to-COPS8P3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA threonylcarbamoyladenosine modification grouped by COPS8P3-low versus COPS8P3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COPS8P3→partner) and Y-score (partner→COPS8P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	tRNA threonylcarbamoyladenosine modification →	+0.042	+0.078	<.001	<.001	3	11
STAD	Obsolete ubiquitin-dependent ERAD pathway →	+0.074	+0.083	<.001	<.001	3	10
STAD	Regulation of DNA strand elongation →	+0.065	+0.075	<.001	<.001	3	10
STAD	Regulation of DNA repair →	+0.076	+0.085	<.001	<.001	3	10
STAD	tRNA metabolic process →	+0.077	+0.093	<.001	<.001	3	10
STAD	Telomere maintenance via telomere lengthening →	+0.072	+0.086	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,190 associations by consensus.

tRNA threonylcarbamoyladenosine modification by COPS8P3 expression — STAD

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