COPS8P3

Across TCGA pan-cancer cohorts, COPS8P3 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of COPS8P3’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where COPS8P3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types COPS8P3 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

LIHC and KICH are the cancer types where COPS8P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in COPS8P3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Male	II,III,IV	+0.084	.012	5	view →
KICH	All	All	−0.089	.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

COPS8P3–LIHC

Open the LIHC breakdown →