COPS7B

Across TCGA patient cohorts, COPS7B RNA expression is significantly associated with the protein abundance of many other proteins, with 13,643 significant associations in total. GBM shows the largest number of these associations.

The most reproducible COPS7B-associated proteins across cancer lineages are SF3B3, ILKAP, and EIF4E2. Each is linked with COPS7B in more than 4 cancer types. Because this analysis shows association rather than direction, both COPS7B-to-partner and partner-to-COPS7B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COPS7B versus SF3B3 in GBM, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COPS7B→partner) and Y-score (partner→COPS7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SF3B3 →	+0.272	+0.268	<.001	<.001	3	5
GBM	ILKAP →	+0.440	+0.355	<.001	<.001	3	5
COAD	EIF4E2 →	+0.274	+0.446	.001	.002	3	5
GBM	GTF2I →	+0.325	+0.188	<.001	<.001	3	5
PDAC	ZNF318_S709 →	+0.498	+0.281	<.001	<.001	3	4
HNSC	SPINDOC_T49 →	+0.563	+0.430	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,643 associations by consensus.

COPS7B vs SF3B3 — GBM

Explore this scatter interactively →