COPS7B

Across TCGA patient cohorts, COPS7B protein abundance is significantly associated with the RNA expression of many other genes, with 7,155 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible COPS7B-associated genes across cancer lineages are NDUFA10, HDLBP, and TRIP12. Each is linked with COPS7B in more than 3 cancer types. Because this analysis shows association rather than direction, both COPS7B-to-partner and partner-to-COPS7B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COPS7B versus NDUFA10 in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COPS7B→partner) and Y-score (partner→COPS7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NDUFA10 →	+0.372	+0.181	.001	.001	3	4
UCEC	HDLBP →	+0.759	+0.215	<.001	<.001	3	4
LUAD	TRIP12 →	+0.402	+0.293	<.001	<.001	3	4
CCRCC	COPS8 →	+0.328	+0.210	.004	.001	3	4
HNSC	ABCB6 →	+0.306	+0.151	.006	.003	2	4
LSCC	AP4M1 →	+0.376	+0.223	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,155 associations by consensus.

COPS7B vs NDUFA10 — BRCA

Explore this scatter interactively →