COMMD7

Across TCGA cell cohorts, COMMD7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,601 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible COMMD7-associated GO terms across cancer lineages are Regulation of proteolysis, IRE1-mediated unfolded protein response, and Biological process involved in symbiotic interaction. Each is linked with COMMD7 in more than 8 cancer types. Because this analysis shows association rather than direction, both COMMD7-to-partner and partner-to-COMMD7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of proteolysis grouped by COMMD7-low versus COMMD7-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COMMD7→partner) and Y-score (partner→COMMD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of proteolysis →	+0.106	+0.992	.002	.004	3	9
STOMACH	IRE1-mediated unfolded protein response →	+0.182	+1.637	<.001	<.001	3	8
STOMACH	Biological process involved in symbiotic interaction →	+0.082	+1.412	.006	.002	3	8
STOMACH	Regulation by virus of viral protein levels in host cell →	+0.161	+1.523	<.001	.001	3	8
STOMACH	Maintenance of location in cell →	+0.070	+1.331	.003	.004	3	8
OVARY	Regulation of plasma membrane organization →	+0.132	+0.709	.003	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,601 associations by consensus.

Regulation of proteolysis by COMMD7 expression — BONE

Explore this box plot interactively →