COMMD7

Across TCGA cell cohorts, COMMD7 mutation is significantly associated with the mutation status of many other genes, with 1,165 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible COMMD7-associated genes across cancer lineages are BICD1, INPP5B, and INO80D. Each is linked with COMMD7 in more than 2 cancer types. Because this analysis shows association rather than direction, both COMMD7-to-partner and partner-to-COMMD7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BICD1 grouped by COMMD7-low versus COMMD7-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COMMD7→partner) and Y-score (partner→COMMD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	BICD1 →	+4.824	+5.392	.004	.004	1	3
BLOOD_Leukemia	INPP5B →	+4.000	+5.050	.008	.008	1	3
BREAST	INO80D →	+4.297	+4.857	.009	.009	1	3
BREAST	ZFP64 →	+4.297	+4.857	.009	.009	1	2
BREAST	FAM184B →	+5.297	+5.297	.004	.004	1	2
BREAST	PFKP →	+4.297	+4.857	.009	.009	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,165 associations by consensus.

BICD1 by COMMD7 expression — SKIN

Explore this box plot interactively →