COMMD5

Across TCGA patient cohorts, COMMD5 protein abundance is significantly associated with the RNA expression of many other genes, with 11,957 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COMMD5-associated genes across cancer lineages are MAN1C1, COLEC12, and PBK. Each is linked with COMMD5 in more than 6 cancer types. Because this analysis shows association rather than direction, both COMMD5-to-partner and partner-to-COMMD5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COMMD5 versus MAN1C1 in OV, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COMMD5→partner) and Y-score (partner→COMMD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MAN1C1 →	+0.705	+0.260	<.001	<.001	3	7
BRCA	COLEC12 →	+0.917	+0.160	.001	.001	3	6
UCEC	PBK →	-1.057	-0.194	.001	.002	3	6
OV	DAB2 →	+1.053	+0.247	<.001	<.001	3	6
GBM	CENPF →	-1.010	-0.196	.002	.002	3	5
UCEC	KIF14 →	-0.793	-0.173	.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,957 associations by consensus.

COMMD5 vs MAN1C1 — OV

Explore this scatter interactively →