COMMD10

Across TCGA patient cohorts, COMMD10 mutation is significantly associated with the RNA expression of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COMMD10-associated genes across cancer lineages are RNA5SP286, RNU6-445P, and CTHRC1P1. Each is linked with COMMD10 in more than 1 cancer types. Because this analysis shows association rather than direction, both COMMD10-to-partner and partner-to-COMMD10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP286 grouped by COMMD10-low versus COMMD10-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COMMD10→partner) and Y-score (partner→COMMD10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNA5SP286 →	+0.297	+7.930	<.001	.008	3	2
LUAD	RNU6-445P →	+0.497	+7.930	<.001	.008	3	2
UCEC	CTHRC1P1 →	+0.125	+3.694	.002	.003	3	1
UCEC	RNU6-206P →	+0.243	+4.437	<.001	.005	3	1
UCEC	RNU6-48P →	+0.633	+2.932	.003	.007	3	1
UCEC	TRGJP1 →	+0.843	+3.063	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

RNA5SP286 by COMMD10 expression — LUAD

Explore this box plot interactively →