COL6A4P1

Across TCGA patient cohorts, COL6A4P1 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COL6A4P1-associated genes across cancer lineages are p27_pT157, eIF4E, and GATA6. Each is linked with COL6A4P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both COL6A4P1-to-partner and partner-to-COL6A4P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p27_pT157 grouped by COL6A4P1-low versus COL6A4P1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL6A4P1→partner) and Y-score (partner→COL6A4P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p27_pT157 →	-0.088	-3.169	.005	.020	3	1
UCEC	eIF4E →	+0.312	+3.169	.007	.020	2	1
UCEC	GATA6 →	-0.217	-2.992	.015	.036	2	1
UCEC	ACVRL1 →	-0.234	-2.980	.001	.036	2	1
UCEC	MEK1 →	+0.544	+3.169	.006	.020	2	1
UCEC	p70-S6K_pT389 →	-0.304	-3.169	.003	.020	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

p27_pT157 by COL6A4P1 expression — UCEC

Explore this box plot interactively →