COL6A4P1

Across TCGA pan-cancer cohorts, COL6A4P1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated COL6A4P1 data layer compared with 2 for mutation status.

The strongest signal is observed in kidney chromophobe (KICH), where higher COL6A4P1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated COL6A4P1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and CHOL show a favorable association.

KICH, HNSC, and ACC are the cancer types where COL6A4P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Median	All	0.644	0.944	<.001	95	view →
HNSC	DFS	Tertile	IV	0.714	0.547	.006	48	view →
ACC	DFS	Median	All	0.245	0.645	<.001	45	view →
KIRC	OS	Median	II,III,IV	0.431	0.599	.002	34	view →
PCPG	DFS	Quartile	All	0.565	0.960	.002	29	view →
MESO	DFS	Tertile	II,III,IV	0.236	0.536	.015	26	view →
LIHC	DFS	Quartile	All	0.333	0.456	.008	25	view →
LGG	OS	Tertile	All	0.314	0.598	<.001	19	view →
CHOL	DFS	Median	All	0.837	0.221	.010	18	view →
PAAD	DFS	Median	All	0.268	0.440	.003	18	view →
CESC	DFS	Tertile	III,IV	0.260	0.772	.018	16	view →
BRCA	OS	Quartile	All	0.896	0.945	.021	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

COL6A4P1–KICH (OS)

Open the KICH breakdown →