COL6A2

Across TCGA patient cohorts, COL6A2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,286 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible COL6A2-associated genes across cancer lineages are SPARC, CD93, and CNN1. Each is linked with COL6A2 in more than 9 cancer types. Because this analysis shows association rather than direction, both COL6A2-to-partner and partner-to-COL6A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL6A2 versus SPARC in BRCA, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL6A2→partner) and Y-score (partner→COL6A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SPARC →	+1.485	+0.797	<.001	<.001	3	10
OV	CD93 →	+0.938	+0.645	.001	<.001	3	10
UCEC	CNN1 →	+1.895	+0.597	<.001	<.001	3	10
OV	MSRB3 →	+1.390	+0.684	<.001	<.001	3	10
OV	CALHM5 →	+0.899	+0.567	<.001	<.001	3	10
HNSC	LINC00702 →	+0.829	+0.581	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,286 associations by consensus.

COL6A2 vs SPARC — BRCA

Explore this scatter interactively →