Across TCGA patient cohorts, COL4A6 mutation is significantly associated with the RNA expression of many other genes, with 4,363 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COL4A6-associated genes across cancer lineages are RNU6-1169P, RN7SKP264, and MCM6. Each is linked with COL4A6 in more than 3 cancer types. Because this analysis shows association rather than direction, both COL4A6-to-partner and partner-to-COL4A6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL4A6→partner) and Y-score (partner→COL4A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RNU6-1169P →	+0.172	+4.479	<.001	.006	3	4
UCEC	RN7SKP264 →	+0.111	+1.579	.001	.001	3	4
UCEC	MCM6 →	+0.490	+2.700	<.001	<.001	3	3
COAD	MTCO2P4 →	+0.142	+3.225	.001	.004	3	3
BRCA	RNA5SP86 →	+0.138	+4.548	<.001	.004	3	3
LUAD	CHST14 →	-0.455	-2.177	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,363 associations by consensus.

Exploration

COL4A6 survival (RNA) · tumor vs normal (RNA) · all COL4A6 data types