COL1A2

Across TCGA patient cohorts, COL1A2 mutation is significantly associated with the RNA expression of many other genes, with 4,647 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COL1A2-associated genes across cancer lineages are PIMREG, AURKB, and RAD51. Each is linked with COL1A2 in more than 5 cancer types. Because this analysis shows association rather than direction, both COL1A2-to-partner and partner-to-COL1A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PIMREG grouped by COL1A2-low versus COL1A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL1A2→partner) and Y-score (partner→COL1A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PIMREG →	+0.601	+1.518	<.001	.001	3	6
UCEC	AURKB →	+0.441	+1.823	.007	.002	3	5
UCEC	RAD51 →	+0.645	+1.776	<.001	<.001	3	5
COAD	CDCA4 →	+0.361	+2.267	.004	<.001	3	5
UCEC	HASPIN →	+0.651	+2.080	<.001	<.001	3	5
SKCM	RCC1 →	+0.396	+2.227	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,647 associations by consensus.

PIMREG by COL1A2 expression — UCEC

Explore this box plot interactively →