COCH

Across TCGA patient cohorts, COCH protein abundance is significantly associated with the protein abundance of many other proteins, with 13,789 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COCH-associated proteins across cancer lineages are EHD1, AP3S1, and ACAT2. Each is linked with COCH in more than 3 cancer types. Because this analysis shows association rather than direction, both COCH-to-partner and partner-to-COCH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COCH versus EHD1 in HNSC, with a Pearson correlation of -0.73.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COCH→partner) and Y-score (partner→COCH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	EHD1 →	-0.488	-1.286	<.001	<.001	3	4
CCRCC	AP3S1 →	-0.235	-0.559	<.001	<.001	3	3
HNSC	ACAT2 →	+0.666	+1.910	<.001	.002	3	3
LSCC	AATF_S320 →	+0.452	+0.774	<.001	.001	3	3
HNSC	CAD →	+0.495	+1.629	<.001	<.001	3	3
HNSC	CAMK2D →	-0.605	-1.713	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,789 associations by consensus.

COCH vs EHD1 — HNSC

Explore this scatter interactively →