COA7

Across TCGA cell cohorts, COA7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,782 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible COA7-associated GO terms across cancer lineages are Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), Mitochondrial RNA metabolic process, and Ribosomal large subunit assembly. Each is linked with COA7 in more than 18 cancer types. Because this analysis shows association rather than direction, both COA7-to-partner and partner-to-COA7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) grouped by COA7-low versus COA7-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COA7→partner) and Y-score (partner→COA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.150	+0.966	<.001	<.001	3	19
BONE	Mitochondrial RNA metabolic process →	+0.111	+0.919	.003	<.001	3	18
LIVER	Ribosomal large subunit assembly →	+0.149	+1.052	.001	.001	3	17
BONE	Maturation of SSU-rRNA →	+0.147	+0.974	<.001	<.001	3	17
PANCREAS	IMP biosynthetic process →	+0.200	+1.204	<.001	<.001	3	17
BONE	DNA replication checkpoint signaling →	+0.185	+0.753	.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,782 associations by consensus.

Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) by COA7 expression — BONE

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