CNTNAP5

Across TCGA patient cohorts, CNTNAP5 mutation is significantly associated with the RNA expression of many other genes, with 9,440 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNTNAP5-associated genes across cancer lineages are B3GNT4, ANKRD39, and HJURP. Each is linked with CNTNAP5 in more than 6 cancer types. Because this analysis shows association rather than direction, both CNTNAP5-to-partner and partner-to-CNTNAP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B3GNT4 grouped by CNTNAP5-low versus CNTNAP5-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTNAP5→partner) and Y-score (partner→CNTNAP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	B3GNT4 →	+0.524	+2.887	<.001	<.001	3	7
SKCM	ANKRD39 →	+0.307	+2.188	<.001	<.001	3	6
UCEC	HJURP →	+0.477	+2.032	<.001	<.001	3	6
UCEC	MTFR2 →	+0.397	+1.317	.001	<.001	3	6
UCEC	KIFC1 →	+0.543	+1.201	<.001	<.001	3	6
UCEC	HMBS →	+0.341	+1.306	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,440 associations by consensus.

B3GNT4 by CNTNAP5 expression — COAD

Explore this box plot interactively →