CNTNAP5

Across TCGA pan-cancer cohorts, CNTNAP5 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of CNTNAP5’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where CNTNAP5 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CNTNAP5 is over-expressed in tumor, although a few such as READ show the opposite, repressed pattern.

KICH, LUSC, and HNSC are the cancer types where CNTNAP5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CNTNAP5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	All	+3.059	<.001	7	view →
LUSC	All	All	+0.273	<.001	5	view →
HNSC	All	All	+0.117	.005	5	view →
LIHC	All	All	+0.024	.003	4	view →
READ	All	All	−0.199	.030	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

CNTNAP5–KICH

Open the KICH breakdown →