CNTNAP5

Across TCGA patient cohorts, CNTNAP5 mutation is significantly associated with the total protein of many other genes, with 102 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNTNAP5-associated genes across cancer lineages are MIG-6, Cyclin-B1, and FASN. Each is linked with CNTNAP5 in more than 4 cancer types. Because this analysis shows association rather than direction, both CNTNAP5-to-partner and partner-to-CNTNAP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIG-6 grouped by CNTNAP5-low versus CNTNAP5-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTNAP5→partner) and Y-score (partner→CNTNAP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIG-6 →	+0.185	+1.716	.003	.003	3	5
UCEC	Cyclin-B1 →	+0.593	+2.938	<.001	<.001	3	5
COAD	FASN →	+0.415	+2.070	<.001	.001	3	5
COAD	GAPDH →	+0.451	+2.321	.001	.004	3	4
UCEC	4E-BP1 →	+0.292	+2.643	<.001	<.001	3	4
LUSC	P-Cadherin →	+0.155	+1.584	.006	.013	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 102 associations by consensus.

MIG-6 by CNTNAP5 expression — LUAD

Explore this box plot interactively →