CNTNAP3

Across TCGA cell cohorts, CNTNAP3 mutation is significantly associated with the RNA expression of many other genes, with 232 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CNTNAP3-associated genes across cancer lineages are OR4X2, UNC5D, and LCE6A. Each is linked with CNTNAP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNTNAP3-to-partner and partner-to-CNTNAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4X2 grouped by CNTNAP3-low versus CNTNAP3-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTNAP3→partner) and Y-score (partner→CNTNAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR4X2 →	+0.013	+4.369	.006	.008	3	2
OESOPHAGUS	UNC5D →	+0.023	+4.017	.001	.007	3	2
SOFT_TISSUE	LCE6A →	+0.030	+4.977	<.001	.002	3	1
SOFT_TISSUE	CARD18 →	+0.482	+4.369	<.001	.008	3	1
OESOPHAGUS	EPB42 →	+0.056	+4.017	.002	.007	3	1
OESOPHAGUS	PLA2G2E →	+0.285	+4.392	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 232 associations by consensus.

OR4X2 by CNTNAP3 expression — SOFT_TISSUE

Explore this box plot interactively →