CNTN4

Across TCGA cell cohorts, CNTN4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,139 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible CNTN4-associated GO terms across cancer lineages are Negative regulation of transcription by RNA polymerase I, Regulation of myoblast fusion, and Regulation of nucleotide-excision repair. Each is linked with CNTN4 in more than 6 cancer types. Because this analysis shows association rather than direction, both CNTN4-to-partner and partner-to-CNTN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of transcription by RNA polymerase I grouped by CNTN4-low versus CNTN4-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTN4→partner) and Y-score (partner→CNTN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Negative regulation of transcription by RNA polymerase I →	+0.169	+1.943	<.001	<.001	3	7
LUNG_SCLC	Regulation of myoblast fusion →	+0.091	+1.849	<.001	<.001	3	7
LUNG_SCLC	Regulation of nucleotide-excision repair →	+0.122	+1.656	<.001	.003	3	7
LUNG_SCLC	Regulation of mRNA catabolic process →	+0.060	+1.868	<.001	<.001	3	7
SOFT_TISSUE	Calcium ion homeostasis →	-0.067	-1.378	<.001	.001	3	7
CNS	Regulation of monoatomic cation transmembrane transport →	-0.058	-0.934	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,139 associations by consensus.

Negative regulation of transcription by RNA polymerase I by CNTN4 expression — LUNG_SCLC

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