CNTN4

Across TCGA cell cohorts, CNTN4 mutation is significantly associated with the RNA expression of many other genes, with 979 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CNTN4-associated genes across cancer lineages are NPHS2, DMRTC2, and CT45A2. Each is linked with CNTN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNTN4-to-partner and partner-to-CNTN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NPHS2 grouped by CNTN4-low versus CNTN4-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTN4→partner) and Y-score (partner→CNTN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	NPHS2 →	+0.010	+3.297	<.001	.008	3	2
BLOOD_Lymphoma	DMRTC2 →	+0.007	+4.058	<.001	.009	3	2
BLOOD_Lymphoma	CT45A2 →	+1.308	+3.843	<.001	.007	3	2
BLOOD_Lymphoma	OR2L8 →	+0.026	+4.169	<.001	.002	3	2
LARGE_INTESTINE	CHMP4B →	-0.552	-2.278	.001	.001	3	2
LARGE_INTESTINE	ATP5F1E →	-0.737	-2.278	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 979 associations by consensus.

NPHS2 by CNTN4 expression — SOFT_TISSUE

Explore this box plot interactively →