CNPY4

Across TCGA cell cohorts, CNPY4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,328 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CNPY4-associated GO terms across cancer lineages are Vacuole organization, Collagen biosynthetic process, and Negative regulation of endodermal cell differentiation. Each is linked with CNPY4 in more than 11 cancer types. Because this analysis shows association rather than direction, both CNPY4-to-partner and partner-to-CNPY4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vacuole organization grouped by CNPY4-low versus CNPY4-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNPY4→partner) and Y-score (partner→CNPY4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Vacuole organization →	+0.057	+0.974	<.001	.002	3	12
CNS	Collagen biosynthetic process →	+0.224	+1.035	<.001	<.001	3	11
SKIN	Negative regulation of endodermal cell differentiation →	+0.784	+0.575	<.001	.002	3	11
OESOPHAGUS	Regulation of glycolytic process through fructose-6-phosphate →	+0.156	+1.424	<.001	.007	3	10
OESOPHAGUS	Negative regulation of glycolytic process through fructose-6-phosphate →	+0.156	+1.424	<.001	.007	3	10
STOMACH	Negative regulation of smoothened signaling pathway →	+0.079	+1.246	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,328 associations by consensus.

Vacuole organization by CNPY4 expression — SKIN

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