CNPY4

Across TCGA cell cohorts, CNPY4 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CNPY4-associated genes across cancer lineages are GML, HHLA1, and LRIT1. Each is linked with CNPY4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNPY4-to-partner and partner-to-CNPY4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GML grouped by CNPY4-low versus CNPY4-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNPY4→partner) and Y-score (partner→CNPY4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GML →	+0.078	+4.152	<.001	.009	3	1
BLOOD_Leukemia	HHLA1 →	+0.011	+4.551	<.001	.004	3	1
BLOOD_Leukemia	LRIT1 →	+0.046	+5.269	<.001	<.001	3	1
BLOOD_Leukemia	GPR26 →	+0.057	+4.539	<.001	.007	3	1
BLOOD_Leukemia	OR1L3 →	+0.085	+4.276	<.001	.007	3	1
BLOOD_Leukemia	TMPRSS7 →	+0.067	+4.276	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

GML by CNPY4 expression — BLOOD_Leukemia

Explore this box plot interactively →