CNPY3

Across TCGA cell cohorts, CNPY3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,758 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CNPY3-associated GO terms across cancer lineages are Positive regulation of transcription initiation by RNA polymerase II, Regulation of transcription initiation by RNA polymerase II, and Negative regulation of amyloid-beta clearance. Each is linked with CNPY3 in more than 9 cancer types. Because this analysis shows association rather than direction, both CNPY3-to-partner and partner-to-CNPY3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of transcription initiation by RNA polymerase II grouped by CNPY3-low versus CNPY3-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNPY3→partner) and Y-score (partner→CNPY3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Positive regulation of transcription initiation by RNA polymerase II →	+0.055	+0.419	<.001	.002	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of transcription initiation by RNA polymerase II →	+0.057	+0.631	<.001	.007	3	9
UPPER_AERODIGESTIVE_TRACT	Negative regulation of amyloid-beta clearance →	+0.116	+0.700	.003	.002	3	8
PANCREAS	Trophectodermal cell differentiation →	+0.121	+0.848	.001	<.001	3	8
BREAST	RNA polymerase II preinitiation complex assembly →	+0.056	+0.645	<.001	<.001	3	8
SKIN	Regulation of metaphase plate congression →	+0.093	+0.472	.009	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,758 associations by consensus.

Positive regulation of transcription initiation by RNA polymerase II by CNPY3 expression — LARGE_INTESTINE

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