CNP

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CNP RNA expression is significantly associated with the protein abundance of many other proteins, with 18,665 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CNP-associated proteins across cancer lineages are DNAJC7, MAP4_S696, and BCAS3_S570. Each is linked with CNP in more than 5 cancer types. Because this analysis shows association rather than direction, both CNP-to-partner and partner-to-CNP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNP versus DNAJC7 in OV, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CNP→partner) and Y-score (partner→CNP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVDNAJC7 →+0.277+0.388.003<.00136
CCRCCMAP4_S696 →+0.606+0.317.004<.00135
LUADBCAS3_S570 →+0.428+0.333<.001<.00135
LUADCMTR1 →+0.248+0.365<.001.00135
LUADEIF2AK2 →+0.302+0.446<.001<.00135
LUADLARP4_S647 →+0.746+0.345.001.00234
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,665 associations by consensus.

CNP vs DNAJC7 — OV

Per-sample scatter of CNP vs DNAJC7 in OV (Pearson r = 0.37).

Explore this scatter interactively →

Exploration