CNP

Across TCGA patient cohorts, CNP protein abundance is significantly associated with the RNA expression of many other genes, with 7,845 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CNP-associated genes across cancer lineages are RAB5C, PSME3, and RNF213. Each is linked with CNP in more than 3 cancer types. Because this analysis shows association rather than direction, both CNP-to-partner and partner-to-CNP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNP versus RAB5C in HNSC, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNP→partner) and Y-score (partner→CNP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RAB5C →	+0.427	+0.134	.002	.001	3	4
LSCC	PSME3 →	+0.649	+0.177	<.001	<.001	3	4
COAD	RNF213 →	+0.765	+0.164	<.001	.007	3	4
LSCC	RUNDC1 →	+0.589	+0.245	<.001	<.001	3	4
LSCC	ATXN7L3 →	+0.536	+0.214	<.001	<.001	3	4
HNSC	CREG1 →	+0.631	+0.117	.003	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,845 associations by consensus.

CNP vs RAB5C — HNSC

Explore this scatter interactively →