CNOT9

Across TCGA patient cohorts, CNOT9 protein abundance is significantly associated with the RNA expression of many other genes, with 12,887 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CNOT9-associated genes across cancer lineages are HJURP, AUNIP, and TROAP. Each is linked with CNOT9 in more than 5 cancer types. Because this analysis shows association rather than direction, both CNOT9-to-partner and partner-to-CNOT9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNOT9 versus HJURP in BRCA, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNOT9→partner) and Y-score (partner→CNOT9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HJURP →	+0.873	+0.163	<.001	<.001	3	6
BRCA	AUNIP →	+0.668	+0.186	<.001	<.001	3	6
LUAD	TROAP →	+0.945	+0.140	<.001	.001	3	6
BRCA	FANCA →	+0.806	+0.280	<.001	<.001	3	6
GBM	EXO1 →	+0.916	+0.223	.004	.003	3	6
LSCC	CDK2 →	+0.621	+0.151	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,887 associations by consensus.

CNOT9 vs HJURP — BRCA

Explore this scatter interactively →