CNOT1

Across TCGA patient cohorts, CNOT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,848 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CNOT1-associated proteins across cancer lineages are CIAPIN1, EDC4, and WWP2. Each is linked with CNOT1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CNOT1-to-partner and partner-to-CNOT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNOT1 versus CIAPIN1 in LSCC, with a Pearson correlation of 0.71.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CNOT1→partner) and Y-score (partner→CNOT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CIAPIN1 →	+0.367	+0.584	<.001	<.001	3	8
GBM	EDC4 →	+0.198	+0.388	<.001	<.001	3	7
LSCC	WWP2 →	+0.272	+0.374	.001	<.001	3	7
LSCC	PSME3IP1 →	+0.333	+0.505	<.001	<.001	3	6
LSCC	SF3B3 →	+0.190	+0.465	<.001	<.001	3	6
HNSC	DHX38 →	+0.351	+0.492	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,848 associations by consensus.

CNOT1 vs CIAPIN1 — LSCC

Explore this scatter interactively →