CNNM2

Across TCGA patient cohorts, CNNM2 mutation is significantly associated with the RNA expression of many other genes, with 3,079 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNNM2-associated genes across cancer lineages are RN7SL794P, DNAJB6P6, and H3P22. Each is linked with CNNM2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CNNM2-to-partner and partner-to-CNNM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL794P grouped by CNNM2-low versus CNNM2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNNM2→partner) and Y-score (partner→CNNM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL794P →	+0.166	+1.365	.001	.005	3	4
KIRP	DNAJB6P6 →	+0.064	+4.497	<.001	.009	3	3
KIRP	H3P22 →	+0.245	+5.301	<.001	.003	3	2
KIRP	RNU6-448P →	+0.234	+4.497	<.001	.009	3	2
KIRP	LSM6P2 →	+0.384	+5.083	<.001	.001	3	2
SKCM	FAM21EP →	+0.303	+3.510	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,079 associations by consensus.

RN7SL794P by CNNM2 expression — UCEC

Explore this box plot interactively →