CNKSR1

Across TCGA patient cohorts, CNKSR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,747 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CNKSR1-associated proteins across cancer lineages are RPS6KA1, RCC1, and LYPLA2. Each is linked with CNKSR1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CNKSR1-to-partner and partner-to-CNKSR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNKSR1 versus RPS6KA1 in LUAD, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CNKSR1→partner) and Y-score (partner→CNKSR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RPS6KA1 →	+0.450	+0.673	<.001	<.001	3	5
LUAD	RCC1 →	+0.379	+0.530	<.001	<.001	3	5
BRCA	LYPLA2 →	+0.305	+0.619	<.001	.001	3	5
LSCC	RCC2 →	+0.370	+0.489	<.001	<.001	3	4
GBM	DNAJC11 →	+0.322	+0.547	<.001	<.001	3	4
LSCC	HDLBP →	-0.306	-0.563	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,747 associations by consensus.

CNKSR1 vs RPS6KA1 — LUAD

Explore this scatter interactively →