CNIH3-AS1

Across TCGA pan-cancer cohorts, CNIH3-AS1 RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated CNIH3-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher CNIH3-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CNIH3-AS1 expression acts as an unfavorable survival marker, although some lineages such as OV and LAML show a favorable association.

UVM, KIRC, and UCS are the cancer types where CNIH3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	All	0.340	0.710	<.001	141	view →
KIRC	DFS	Tertile	All	0.464	0.667	<.001	116	view →
UCS	OS	Quartile	II,III,IV	0.170	0.602	<.001	108	view →
KICH	OS	Tertile	II,III,IV	0.653	0.967	<.001	78	view →
THYM	DFS	Tertile	All	0.652	0.914	<.001	51	view →
OV	OS	Median	IV	0.535	0.289	.006	50	view →
LAML	DFS	Tertile	All	0.623	0.255	.003	36	view →
LGG	DFS	Median	All	0.781	0.880	<.001	30	view →
KIRP	OS	Tertile	III,IV	0.569	0.809	.024	27	view →
THCA	DFS	Quartile	III,IV	0.768	0.985	<.001	27	view →
STAD	DFS	Quartile	II,III,IV	0.289	0.595	.017	25	view →
PAAD	OS	Median	All	0.515	0.270	.001	24	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

CNIH3-AS1–UVM (DFS)

Open the UVM breakdown →